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Lipibec (Atorvastatin)
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Atorvastatin

To investigate the effects of Lipibec (AVT) on renal function and renal pathological changes in the aged rat and explore their possible mechanisms. Effects of Lipibec on the proliferation and collagen synthesis of rat cardiac fibroblasts Left ventricular remodeling induced by AV fistula was profoundly changed by Lipibec treatment.

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Lipibec is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Lipibec is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. Lipibec may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Lipibec is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with Lipibec has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks.

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DARS2 gene clinical spectrum: new ideas regarding an underdiagnosed leukoencephalopathy. Experimental data sets from literature are used for the model validation.

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The diagnostic significance of cells and crystals found in nasal smears is explained. Histopathological, immunohistochemical and molecular analyses of the biopsies were performed.

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This enzymatic activity seems to be directly linked to the biosynthesis of toxins. Currently, epigenetic research is looking for disruption in one or more epigenetic mechanisms to provide new insights into autoimmune diseases.

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The techniques outlined here are demanding and should be carried out by experienced surgeons. Ganglion cells were intracellularly injected with Neurobiotin, visualized with Streptavidin coupled to FITC, and subsequently stained with subunit specific antibodies. The risks of undiagnosed cancer vs the theoretical risks of radiation exposure. Local radiation dose and solid second malignant neoplasms after childhood cancer in Germany: a nested case-control study. However, cold exposures produce significant decreases in core body temperature when the circadian rhythms of the animal are free-running in the absence of environmental time cues.

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Selective occlusion of blood supply to the anterior perforated substance of the dog: a highly reproducible stroke model. The long-term results of the various treatment options are not well defined. Record-linkage and capture-recapture analysis of three TB-related registers: a notification register, a laboratory register and a prescriptions register.

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In these mIBDVs we replaced the region of CEF94 encoding one of the viral proteins (pVP2, VP3, or VP4) by the corresponding region of D6948. We evaluated the prevalence, number and location of CBMs in a cohort of 26 consecutive cerebral hemorrhage patients admitted in the National Institute of Neurology and Neurovascular Diseases. Interestingly, when patients are treated, it was the last sign to disappear.

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Neurosurgeons have been well trained to perform a great number of surgical techniques of neuromodulation, even including helping to significantly increase biomedical activities and the application of high technology to the central and peripheral nervous system. Intestinal ischemia can cause intestinal damage in gastroschisis. The authors present results of studies of application of polyurethane foam to produce individual sound-absorbing ear plugs.

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Gene expression in chorionic villous samples at 11 weeks of gestation in women who develop preeclampsia later in pregnancy: implications for screening. Patients with irritable bowel syndrome: health status and use of health care services.

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Thus, we assessed the possibility that exosomes could transport microRNA- 29c as a carrier and correlations between microRNA-29c and apoptosis of bladder cancer cells. A few different models have been proposed for identifying regional and structural homology between the avian and mammalian hippocampus however a consensus is yet to be reached. Co-immunoprecipitation demonstrated an association between MFN2 and MNS1 in spermatogenic cells. Transcriptional whole-genome microarray profiling suggested alterations in metabolic pathways.

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Protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rats. The necessary shift from a Th2 preferred capacity in late gestation to a more balance functional capacity in the neonate can be disrupted by xenobiotics leaving the child with increased vulnerability to a range of potential diseases.

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One potential cause of aging is the progressive accumulation of dysfunctional mitochondria and oxidative damage with age. Neuronal evidence shows that (i) the identities of activated sensory neurons convey information about the vertical coordinate of an object, (ii) the timing of their firing, in relation to other reference signals, conveys information about the horizontal object coordinate, and (iii) the intensity of firing conveys information about the radial object coordinate. A total of 98 patients with type 2 diabetes and 47 control participants underwent neuropsychological evaluation. Oncology nurses will need to be cognizant of the risks, benefits, and current guidelines related to lung cancer screening as they support patients and their families making informed decisions about personal health care. SDF-1alpha was shown to function as a B-cell maturation factor, a ligand for the CXCR4 (LESTR/fusin) chemokine receptor, thereby inhibiting replication of T cell-tropic HIV-1 strains and inducing cell death in human neuronal cell lines.

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Inference of phylogenetically conserved and derived transcripts demonstrates the power of comparative transcriptomics to trace placenta evolution and variation across mammals and identified candidate genes that may be important in the normal function of the human placenta, and their dysfunction may be related to human pregnancy complications. The interplay between benzene and stem cells is complex involving the stem cell, progenitor, and HSC niche compartments of the bone marrow.

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Western blot analysis of NMDA receptor subunits indicates a higher NR2A/NR2B ratio in Cx36 knockout mice, indicating that there is shift in the threshold for LTP induction in knockout animals. It was also ascertained that low umbilical venous blood flow is a bad prognostic sign because it indicates that the fetus receives an abnormally low quantity of originated blood from the placenta, as was the case of the fetus with DIUG or in the final stages of hypoxia, and that when this happens, the fetus is already incapable of controlling the compensatory circulatory mechanisms and is at imminent risk of cardiac damage.

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Constraint-induced movement therapy (CIMT) is a potentially effective intervention for children with hemiplegic cerebral palsy (CP). This paper describes the effects of a single and a repeated application of the organophosphorus insecticide chlorpyrifos on zooplankton and phytoplankton communities in outdoor microcosms in Thailand. Previously, we reported that an optimal dose of lipopolysaccharide (LPS) markedly extends the life span of mouse primary-cultured microglia by suppressing apoptotic and autophagic cell death pathways.

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Optimization of the conditions for beta-galactosidase biosynthesis in eukaryotes Two-dimensional simulation of the single-sided air-coupled ultrasonic pitch-catch technique for non-destructive testing.

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Strains of different species including close phylogenetic relatives such as S. However, in HepG2, activation of MEKK1 and TAK1 is essential for TGFbeta-induced signal transmission.

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Clinical and laboratory studies on bronchial asthma in 200 Nigerian children who were seen during a 2 1/2-year period in Ibadan are described. These results are new to the literature and shed light on the importance of adopting a full life course approach and capturing sex differences when evaluating the long-term impacts of early life exposures.

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No correlation of latent CHPI to either current or past genital warts was noted. By 24 h of exposure, there was a pronounced inflammatory response to ROFA instillation and a marked increase in levels of P-Tyr and P-MAPKs present within the alveolar epithelium and in the inflammatory cells, while the airway epithelium showed a continued increase in the expression of P-ERK1/2. Residual varus alignment does not compromise results of TKAs in patients with preoperative varus. Insulin-stimulated glucose transport is dependent on Golgi function in isolated working rat heart. Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury.

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Longitudinal surveillance biopsy studies have revealed a substantial burden of subclinical immunological and non-immunological injury, including acute cellular rejection, interstitial fibrosis and tubular atrophy, microvascular lesions and transplant glomerulopathy. However, disaster research has been disproportionately focused on units of analysis such as families, households and government agencies.

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Muscle biopsies were obtained for histopathologic evaluation, protein gel electrophoresis, immunofluorescence, and complement staining. We found that although some TCRs were shared, the TCR repertoires selected by mice receiving splenocytes from the same donor were not identical in terms of the TCRs selected and their relative frequencies. Cases were compared with 159 control biopsies from the years 2005-07 matched by patient age and CIN grade. The chaetotaxy and ciliated cells in two Monogenean larvae of marine fishes are described for the first time: a Monopisthocotylea Diplectanum aequans (Wagener, 1857) Diesing, 1858 parasite of Dicentrarchus Labrax (L) and a Polyopisthocotylea, Microcotyle mormyri Lorenz, 1878 parasite of Pagellus mormyrus (L). The authors retrospectively identified 188 patients with ventricular-region AVMs who underwent a single-stage GKS procedure during a 22-year interval.

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Recombinant probiotics with antimicrobial peptides: a dual strategy to improve immune response in immunocompromised patients. Comparative analysis of health state of population in Novgorod region in 1985 and 2005 years was performed.

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New genus of the tribe Diestramimini (Orthoptera: Rhaphidophoridae) from Thailand. Maximum number of target lesions required to measure responses to transarterial chemoembolization using the enhancement criteria in patients with intrahepatic hepatocellular carcinoma.

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This analysis base case was modeled for a tertiary care, teaching hospital. Fundamental motor skill proficiency of Hong Kong children aged 6-9 years. Effect of abamectin exposure on semen parameters indicative of reduced sperm maturity: a study on farmworkers in Antalya (Turkey). All patients underwent percutaneous vertebroplasty (PVP) or balloon kyphoplasty (BKP) when conservative treatment failed to offer pain relief.

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The literature concerning the potential use of emergency US in the pre-hospital setting is evaluated. The antithrombotic effects of warfarin and heparin following infusions of tissue thromboplastin in rabbits: clinical implications. Traditional Granger causality is based on vector autoregressive (AR) or mixed autoregressive moving average (ARMA) model, which are potentially affected by errors in parameter estimation and may be contaminated by zero-lag correlation, notably when modeling neuroimaging data. On the other hand, a dopaquinone analogue, 4-(2-N-acetylaminoethyl)-1,2-benzoquinone, synthesized from N-acetyl dopamine, was demonstrated to have marked affinity for this sulfhydryl enzyme.

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The percentage of activated LNc was lower in mixed leukocyte reactions (MLR) added with seliciclib than in MLR added with vehicle. The effect of different methods of photohemotherapy on the rheological properties of the blood in patients with ischemic heart disease Frequency polygons of the attenuation coefficients for each of five brain slices have been constructed. Mutations in Flavobacterium johnsoniae sprE result in defects in gliding motility and protein secretion. To search for single-nucleotide polymorphisms in the interleukin-8 (IL-8) and IL-8 receptor CXCR-1 and CXCR-2 genes, and to compare their distribution among patients with systemic sclerosis (SSc) with fibrosing alveolitis (FASSc) or without fibrosing alveolitis (NFASSc), or patients with cryptogenic fibrosing alveolitis (CFA), and normal healthy subjects.

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TLR-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis. RESULTS APROPOS OF 221 OPERATIONS, OF 204 PACEMAKERS IMPLANTED IN 161 PATIENTS is described, and illustrations provided as well as distributional records and a discussion of its possible phylogenetic affinities.

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The Ehlers-Danlos syndrome (EDS) is a rare inheritable disease, characterised by a defect in collagen synthesis. Differences in plasma glucose, insulin, triglyceride, apolipoprotein B, high-density lipoprotein cholesterol, and nonesterified free fatty acid levels were assessed using mixed models and 24-h incremental areas under the time-concentration curve. Thirty patients with AOGHD were compared with 30 age-, sex-, body mass index-matched controls with respect to endocrine evaluation, biochemistry, body composition (BC), bone mineral density (BMD), cardiovascular risk profile and quality of life (QoL). The extended algorithm is referred to as generalization of SLIM (GoSLIM). Here, we functionally characterized an effector PsCRN70 by transiently and stably overexpressing it in Nicotiana benthamiana.

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The levels of MCP-1 and RANTES in the incubation medium were determined by enzyme-linked immunoabsorbent assay (ELISA). Because of its size, this study provides limited data on any difference in toxicity between the regimens, but toxicities were manageable and reversible. The non-surgical intervention is promoted before undertaking major surgery.

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Since a short-term (5-min) incubation with analogue (V) reduced the KGF-induced tyrosine phosphorylation of a 120-kDA protein, corresponding to the KGF receptor, a rapid and direct cross-talk between these two molecules is suggested. Subarachnoid buprenorphine administered by implantable micropumps.

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The IXP approach integrates both gene expression information and organized knowledge - disease gene/protein network topology information, which is represented as both network node weights (local topological properties) and network node orders (global topological characteristics). Rehabilitation in the Veneto Region: towards a logic of clinical governance A decision-analytical model represented direct costs and PAE rates, mortality, and costs. The damage to small intestine induced by chronic alcohol treatment was examined by intestinal histological, immunohistochemical analysis, and permeability assays. NEOPLASMS OF gelnique dosing system THE VULVA IN THE RECORDS OF THE INSITITUE OF ONCOLOGY OF GLIWICE IN THE PERIOD 1947-1957

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