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Tolterodine is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency and frequency. It is available by prescription only in a 2 and 4 mg extended release capsule formulation. The FDA approved Tolterodine in 1998. An extended release form of Tolterodine, (Tolterodine LA) was approved by the FDA in 2001.

Other names for this medication:
Tolterodine, Detrol, Roliten, Detrusitol, Flochek,

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Tolterodine is used treat overactive bladder (a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination). Tolterodine is in a class of medications called antimuscarinics. It works by relaxing the bladder muscles preventing bladder contraction.

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Standard tests of intelligence (Wechsler Intelligence Scale for Children-Revised, WISC-R), academic potential (Metropolitan Readiness Test, MRT), and spatial integration (Bender Visual Motor Gestalt Test, BVMGT) also were given. Prognostic significance of PTEN, Ki-67 and CD44s expression patterns in gastrointestinal stromal tumors. A cross-sectional validation study of using NERDS and STONEES to assess bacterial burden. Expression of transforming growth factor beta 1 and conection tissue growth factor in ankylosing spondylitis They were much less frequent during the 80-200 msec pause in tonic afferent input that follows the excitation evoked by cortical or thalamic stimulation, and were decreased in frequency in decorticate animals.

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In silico evaluation of glucose control protocols for critically ill patients. The inhibition of protein secretion or deletion of IL-10 cancelled the effect of rapamycin, indicating that mTOR regulates IL-12 expression through an autocrine action of IL-10. In cases of strangulation by ligature, hemorrhage and edema of the cochlear duct in the inner ear as well as hemorrhage in the mastoid air cells were demonstrated bilaterally. Participants were randomly assigned to one of three active treatments (walking, light, combination treatment) or contact control and received three or six in-home visits. Literacy level may be a more specific indicator of risk than educational level in low-income families.

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We used data sets of experimentally identified acetylation and phosphorylation sites in Drosophila and humans to analyze the evolutionary conservation of these modification sites between flies and humans. This conclusion is based on short and medium term trials (up to 24 weeks). The persistence of the precursor form of S40 may be functionally significant as well. Thus we propose that kinesin I, in concert with centralspindlin complex, plays a role in temporal and spatial regulation of endosome transport to the cleavage furrow during cytokinesis.

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Fatty acid-induced gut-brain signaling attenuates neural and behavioral effects of sad emotion in humans. In the present in vivo study, there was a higher rate of root canal filling extrusion using Thermafil compared to warm vertical compaction. The research shows that veterinarians think more in a product-oriented way than in a market-oriented way, and they do not use all the opportunities a marketing orientation could bring to their services. Effects of the industrial methods of preservation and transformation on the nutritional value of nutrients

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This case demonstrates that contrast enhanced ultrasound (CEUS), employed in addition to computed tomography angiography, offers a promising new option for diagnosis and preoperative treatment planning in patients with abdominal vascular diseases. Both binding of ANX1 to U937 cells and ANX1-mediated inhibition of cell adhesion involved the short N-terminal domain of the ANX1 molecule. Functional CLR-1 was necessary for expression of clr-2 and efficient cellobiose utilization. At present, the reasons for these unexpected connections are only hypothetical, and require further exploration in larger samples, but there is perhaps a multitude of them. A fast-growing variant with time between passages of 2-3 weeks appeared in one mouse on the third passage (f-HC).

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Six patients with severe craniofacial deformities who had bilateral cleft lip-cleft palate were excluded. Field observations to determine the influence of population size, location and individual factors on pedestrian walking speeds.

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Previous studies reported heterogeneous results on the relative frequency of staining in various pathological conditions of the thyroid. The nature of nuclei and fiber tracts in relation to the differential patterns of AChE and BChE is discussed. Neonatal responses (520) were obtained from three different screening sites.

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The article presents the discuss of cause-and-effects conditions between the morphological changes in central nervous system, influence of stress-factors and advance of disease. Autologous bone marrow transplantation in the treatment of selected human malignancies: The Johns Hopkins Oncology Center Program.

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Only 11 percent of abnormal tests (1.3 percent of total tests) might have caused a seizure. While the field of perioperative genomics could be considered in its infancy, such approaches are the wave of the future. Adding to the clinical and molecular heterogeneity of TRPV4-associated diseases, our results suggest that molecular testing of the TRPV4 gene is warranted in cases of congenital dSMA with bone abnormalities and vocal cord paralysis. All subjects were interviewed regarding their diet, previous pregnancies, significant sickness, and medications.

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Cells from the bone marrow are considered important during the rotator cuff repair process, but the kinetics of bone marrow-derived cells in this process is unknown. The first group, Treatment with Support, involved students from schools that implemented a school-based anti-bullying intervention with additional support from the research group.

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Labeled axons originating in these various regions of the frontal lobe have topographically diverse ipsilateral and contralateral destinations but virtually all of these projections share a common mode of distribution: they terminate in distinct vertically oriented columns, 200-500 mum wide, that extend across all layers of cortex and alternate in regular sequence with columns of comparable width in which grains do not exceed background. For both substances the TE groups showed a slight increase (deterioration) in the simple reaction-time task during chemical exposure, but not in the complex reaction-time task or in the digit symbol test of the Wechsler Adult Intelligence Scale.

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The ontogenesis of the dopaminergic cell in the pre- and postnatal guinea pig retina. Epidemiologic significance of primary resistance in Spain: refutation of the concept of transmission of resistant strains of mycobacterium tuberculosis.

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IGF-1R protein expression was measured by Western blot, and IGF-1R mRNA expression by quantitative PCR. HIP-55 was overexpressed and knocked down in cardiomyocytes with an adenovirus infection. Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications. Patients reported feeling better informed and more involved in their treatment, and staff said that they became more thoughtful about their notes in the chart.

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Prospective matched-pair comparison of outcome after treatment for lobular and ductal breast carcinoma. Physical activity and memory functions: an interventional study. Furthermore, family caregiving can be associated with negative physical, financial and psychosocial outcomes. To test their clinical impression they systematically compared the medical histories of 20 delinquent children with criminal parents and 85 delinquent children with less obviously maladapted parents. Although acquired factor X deficiency after HDM/ASCT for MM with systemic AL amyloidosis is rare, we should be aware of the possibility of this disease in MM patients with a bleeding tendency.

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Our results demonstrate the functional utility of peripheral prism glasses as a general mobility aid for patients with hemianopia. Twenty-year follow-up of bulimia nervosa and related eating disorders not otherwise specified. We report that dexamethasone increases both retinoid X receptor-alpha (RXRalpha) and PXR mRNA expression in cultured human hepatocytes, whereas PXR activators such as rifampicin and clotrimazole do not. At autopsy, there was extensive myelofibrosis associated with neoplastic infiltrates of plasma cells in both cases. Gefitinib in the treatment of refractory non-small cell lung cancer

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On schizophrenia prognosis based on data of a clinicogenetical study. This study aimed to correlate the total and differential cell counts, CD4:CD8 ratio, and tumour necrosis factor (TNF)alpha levels between induced sputum and BAL fluid in patients with pulmonary sarcoidosis.

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Treatment of glioblastoma remains a challenge in neuro-oncology. Kinematics of preferred and non-preferred handballing in Australian football. Analysis by surface plasmon resonance demonstrated that various growth/differentiation factors specifically bound to the shrimp HS with comparable affinity. Sessions of morphine or cocaine presentation, each with distinct stimulus light conditions, alternated on a daily basis.

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