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Twenty-four patients with severe stable angina pectoris were included in a randomized, double-blind, placebo-controlled, cross-over study to assess the efficacy of a controlled-release preparation of Isosorbide-5-mononitrate (ISMN-CR) 60 mg once daily or twice daily as adjunctive treatment to a beta blocker.

Other names for this medication:
Isosorbide, Isordil,

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Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Isosorbide is in a class of medications called vasodilators. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen.

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The self-arrangement of the methylthiolate-adatom complexes on the surface depends critically on their stereochemical properties. Each technique resulted in specific and different findings on the POD 1 esophagram.

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We compared the effect of the program on 30-day (from discharge) all-cause readmission rate, length of stay, and 60-day (from admission) direct cost for BMCG with that of other hospitals within the Baylor Health Care System. Accurate communication among providers-and between the patient and providers-is important to avoid misinformation or misunderstandings in the care of patients with complicated problems.

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During its course, over 26 separate scenes with from one to five victims each have been processed. Tissue-antigens detected by autoantibodies in synovial fluid and sera of RA patients. The combination of cTEE and cTCD could be considered the real gold standard for PFO in the near future.

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Paired t tests were carried out to further clarify the separation between the EEG patterns of NCSE and TME. These latest findings shed light on the novel roles of Nur77 as an exploitable target for new cancer therapeutics. However, the role of WWP1 in cellular senescence is still unknown. Use of S100b protein for optimization of cornea regeneration after surgery Moreover, a concerted effort is needed to ensure the development and future availability of appropriate vaccines for Africa.

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Screening has also resulted in the diagnosis of low-grade, less-aggressive prostate cancers which would probably never lead to complications or death from the disease. The measurement is used to control a sensory feedback device applied to the surface of the skin within the socket of the prosthesis informing the wearer of the strength of grip exerted. It is suggested that the level of membrane potential is either directly or indirectly responsible for the level of mitochondrial anion conductivity.

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A secondary aim was to study whether pulmonary shunt correlates with cardiac output (CO). The major enantiomer formed in the reduction of six-membered alkenes could be predicted from a selectivity model and isomeric alkenes had complementary enantioselectivity, giving opposite optical isomers upon hydrogenation. The results obtained showed that the both variants of the gypsy protein Gag form globular particles in the bacterial cell. The increasing incidence of Candida yeasts infections and its hospital and community repercussion (vaginal thrush), as well as the will to acquire the knowledge of the new antifungal that were launched to the therapeutic store, have motivated us to identify that type of yeasts from different sources, as well as to study their behaviour against the antifungal, using commercial procedures with easy clinical application. These variables could potentially be used to develop treatment algorithms that tailor therapies for specific clinical situations.

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The study highlights the importance of nurse managers in creating the communication culture that will allow nurses to speak up and be heard. Mechanism involved in production of immunological paralysis by type I pneumococcal polysaccharide. The growth of a thin film on a flat substrate by LbL was monitored by UV-vis spectra.

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STRO-1 positive hPDLCs were sorted and the sorted cells were expanded and compared with their unsorted parental cells. Allele and genotype frequencies, as well as homo-heterozygote distributions were compared between the two groups of 309 bipolar affective disorder patients and 309 matched controls. Early results following radical prostatectomy in patients with capsule invasion, seminal vesicle infiltration and micrometastases The vascular endothelial growth factors are key mediators of angiogenesis and are also related to several physiological processes such as monocyte chemotaxis, dendritic cell development, hematopoietic stem cell survival, and many others.

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Since deterministic models cannot provide analytical solutions for the moments of drug concentration distribution functions, stochastic models can be used to provide useful insights into the design of therapeutic regimens. In order to study the location of the single cysteinyl residue in the primary structure of yeast 3-phosphoglycerate kinase, cyanylation by 2-nitro-5-thiocyanobenzoic acid has bben carried out. Substitutional mechanism of Ni into the wide-band-gap semiconductor InTaO4 and its implications for water splitting activity in the wolframite structure type.

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The results showed that the extent and pattern of growing neurites of cortical explants varied considerably depending on the substrata used. Effects of DNase production, plasmid size, and restriction barriers on transformation of Vibrio cholerae by electroporation and osmotic shock. The main aim of the current study was to quantify the unique effect of acute exposures on next-hour suicidal ideation when adjusting for previous hour acute exposures and suicidal ideation. Relaxation of a transfer RNA specificity by removal of modified nucleotides. Transcultural reflection on clinical teaching using an experiential teaching-learning model.

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Abstracts of the XI Congress of the Spanish Association of Gastroenterology. Apicomplexan parasite, Eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouse. BHT-3009 is a tolerizing DNA vaccine for MS, encoding full-length human myelin basic protein. The (relative) contribution of transmission routes that might play a role in the dissemination of ESBL/AmpC-encoding resistance genes to humans on broiler farms should be pursued in future studies. The molybdenum complex was found to yield higher absorbance compared to antimony and bismuth complexes of various flavonoids.

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Dimorphic aggregation behavior of a fusion polypeptide incorporating a stable protein domain (EGFP) with an amyloidogenic sequence (retroCspA). In addition, HIV seropositive children had a 10 per cent prevalence of abnormal visual acuity compared with HIV seronegative children who had a 6 per cent prevalence. To investigate the dimensionality, reliability and construct validity of the Hospital Anxiety and Depression scale (HADS) in a cognitively intact nursing home population.

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Data from sentinel travelers upon their return to medically sophisticated environments can also benefit local populations in resource-limited countries. Our aim was to conduct a meta-analysis of prospective studies to assess the relation between potassium intake and stroke risk. Interventions that examined mediators of dietary behavior change in youth (age 5-18 years) were identified via electronic database searches and reference scanning. The ATP-binding cassette (ABC) transporters ABCA1 and ABCG1 regulate macrophage cholesterol efflux and hence play a vital role in macrophage foam cell formation.

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Evaluation for epilepsy surgery disclosed two independent epileptic foci, one limbic and the other nonlimbic. One of the first investigations concerning extracorporeal treatment of hypercholesterolemia was performed in 1967 by plasma exchange in patients with homozygous or severe heterozygous familial hypercholesterolemia (FH). It is also shown that energy trapping is sensitive to the geometric and physical parameters of the structure. These results suggest that unlike perivascular noradrenergic nerves supplying the cerebrovascular tree, the sympathetic innervation of spinal cord blood vessels does not undergo age-dependent changes. The administration of adolescent chronic stimuli to males decreased the adult plasma corticosterone (CORT) and progesterone levels after restraint.

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This video demonstrates the regional anatomy pertinent to the anterior abdominal wall, specifically of the umbilicus. The detection of positive selection pressure in the non-structural protein along genotype II indicated that DENV-3 originated from Southeast Asia needs to monitor the emergence of DENV strains with epidemic potential for better epidemic prevention and vaccine development. In addition, the results provide evidence of the applicability of the scale to normal adult and clinical samples.

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Lifetime history of exposure to dental x-rays on five or more occasions was associated with significantly increased risk of laryngeal cancer among heavy smokers but not among light smokers. A survey of deer brought to tagging stations at 24 sites in Main revealed the presence of the deer tick, Ixodes dammini, on 5.1 percent of deer. Both genetic and environmental factors play role in the pathogenesis of the metabolic syndrome. led to the isolation of three new spirobisnaphthalene analogues, spiropreussione A (1), spiropreussione B (2), and spiropreussomerin A (3).

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The purpose of this study was to investigate the acoustic changes in articulation of corner vowels in deaf children and adults after cochlear implantation. Adenomyofibroma of the endometrium with skeletal muscle differentiation. Through the improved access to multibeam sonar and underwater video technology these models provide spatial predictions of the most suitable regions for an organism at resolutions previously not possible.

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Multiphoton photochemical and collisional effects during oxygen-atom flame detection. Alpha blocker therapy seems well tolerated in children and appears efficacious towards improving bladder emptying in a variety of pediatric voiding disorders. Standardising measurement of tumour vascularity by imaging: recommendations for ultrasound, computed tomography, magnetic resonance imaging and positron emission tomography. Sparing effect of folic acid deficiency on the development of vitamin B12 deficiency in baboons fed a vitamin B12 deficient diet.

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We identified several behaviors that varied between clonal lines and QTL for several behavioral and size traits. Bile acids in human breast cyst fluid: the identification of lithocholic acid.

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Glutathione levels in human lens: regional distribution in different forms of cataract. The incidence of pineal calcification was studied by reviewing skull radiographs of 1400 patients admitted to a major neurosurgical centre at Karachi over an eight year period.

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Modulation of human muscle spindle discharge by arterial pulsations--functional effects and consequences. In-flight canopy loss in high-speed fighter or trainer aircraft poses serious aeromedical problems for the crew-members. The role of endothelin-1 and nitric oxide in the pathogenesis of hypertension in diabetic patients.

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Behavioral and environmental objectives were developed and led to a culturally tailored nutrition intervention. The diagnosis and treatment of generalized cytomegalic inclusion disease of the newborn. The mechanisms of HER fluzone mdv package insert on the fabricated substrates were studied by Tafel analysis and electrochemical impedance spectroscopy (EIS). Subcortical volumes in girls with tourette syndrome: support for a gender effect.

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